Nearly all SLE patients Patients with SLE more frequently had skin problems, serositis inflammation of the tissues lining the lungs, heart, and the inner lining of the abdomen , synovitis inflammation of a type of membrane that lines the joints , kidney disease, low levels of white blood cells lymphocytes , and generalized inflammation. Regular checks for dry eyes and dry mouth, known as sicca symptoms, is easy and can also help to differentiate the two conditions, the researchers said.
Envelope icon Subscribe to our newsletter Get regular updates to your inbox. Your Email. In an open label study of hydroxychloroquine, several SS patients improved [ 26 ]. SLE is effectively treated with hydroxychloroquine. This large difference in response to hydroxychloroquine suggests that SLE and SS are significantly dissimilar. SLE has a similar sexual ratio. Sexual epidemiology does not help distinguish these diseases. There is clinical evidence that SS and lymphoma are linked. However, it can also occur in the lymph nodes or bone marrow.
The weight of evidence is that SS and lupus are distinct conditions. SS is linked to lymphoma very strongly and SLE is not. SS and SLE do have similarities. Their autoantibody profiles are not dissimilar. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. Systemic lupus erythematosus disease activity index Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus.
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